By Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
The Chemistry and Biology of Nitroxyl (HNO) offers first-of-its-kind assurance of the interesting biologically lively molecule known as nitroxyl, or azanone in line with IUPAC nomenclature, which has been generally elusive because of its intrinsically excessive reactivity.
This resource presents the medical foundation to appreciate the chemistry, biology, and technical points had to care for HNO. construction on twenty years of nitric oxide and nitroxyl study, the editors and authors have created an critical consultant for investigators throughout a wide selection of parts of chemistry (inorganic, natural, organometallic, biochemistry, actual, and analytical); biology (molecular, mobile, physiological, and enzymology); pharmacy; and medicine.
This publication starts off by means of exploring the original molecule’s constitution and reactivity, together with very important reactions with small molecules, thiols, porphyrins, and key proteins, ahead of discussing chemical and organic assets of nitroxyl. complicated chapters talk about equipment for either trapping and detecting nitroxyl by means of spectroscopy, electrochemistry, and fluorescent inorganic mobile probing.
Expanding at the compound’s foundational chemistry, this e-book then explores its molecular body structure to supply perception into its organic implications, pharmacological results, and functional issues.
- Presents the 1st booklet on HNO (nitroxyl or azanone), an more and more vital molecule in biochemistry and pharmaceutical research
- Provides a precious insurance of HNO’s chemical constitution and critical reactions, together with useful information on operating with this hugely reactive molecule
- Contains prime quality content material from famous specialists in either and academia